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CHEWABLES FOR CATS
CAUTION: Federal (USA) law restricts this drug to use by or on the order of
delayed, whether by a few days or many, immediate treatment with HEARTGARD for Cats and resumption of the recommended dosing regimenwill minimize the opportunity for development of adult heartworm.
INDICATIONS: For use in cats to prevent feline heartworm disease by
eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a
It is recommended that cats should be tested for existing heartworm month (30 days) after infection, and for the removal and control of adult and infection prior to starting treatment with HEARTGARD for Cats. Cats already immature hookworms (Ancylostoma tubaeforme and A. braziliense).
infected with adult heartworms can be given HEARTGARD for Cats monthlyto prevent further infections.
DOSAGE: HEARTGARD® (ivermectin) for Cats should be administered orally
at monthly intervals at the recommended minimum dose level of 24 mcg of
Monthly treatment with HEARTGARD for Cats also provides effective ivermectin per kg (10.9 mcg/lb.) of body weight. The recommended dosage removal and control of adult and immature hookworms (A. tubaeforme and schedule for prevention of feline heartworm disease and control of SAFETY: In the clinical studies involving more than 3000 doses of
HEARTGARD for Cats, observations reported within 24 hours of treatment
Cat Weight
HEARTGARD for Cats
Ivermectin
included vomition in ≤ 0.3% and diarrhea in ≤ 0.2% of the doses Chewables per month
administered. There were no statistical differences between HEARTGARD for Cats and the product vehicle (control) for these observations.
A wide margin of safety was demonstrated in clinical trials at therecommended dose level in cats and kittens 6 weeks of age and older and in For cats over 15 lb., use the appropriate combination of chewables.
laboratory studies in cats with circulating microfilariae of D. immitis. A wide margin of safety has also been demonstrated at 3 times the recommended HEARTGARD for Cats is recommended for use in cats 6 weeks of age and older.
dose in pregnant or breeding queens and breeding toms. No adverse effectswere observed in either male or female cats or their offspring in breeding ADMINISTRATION: Remove only one chewable at a time from the foil-
studies. A 30-fold safety margin over the minimum recommended dosage backed blister card. Return the card with the remaining chewables to its box was established in a single dose tolerance study. In growing kittens dosed to protect the product from light. HEARTGARD for Cats can be offered to the monthly for 8 consecutive doses, one cat given 5 times the market dose cat by hand or may be added to a small amount of cat food. If manual dosing vomited and a second cat in this group experienced diarrhea within 24 hours is required, the chewable should be broken into pieces for administration.
of the initial treatment. In clinical trials, many commonly used flea control Food should be routinely available during the day of treatment administration.
products, anthelmintics, vaccines, antibiotics and steroid preparations were If cats are fasted, or if the chewable is not broken into pieces for manual administered with HEARTGARD for Cats without incident.
dosing, then reduced absorption may result. A relationship between reducedabsorption and reduced efficacy has not been established.
Keep this and all drugs out of the reach of children. In case of
ingestion by humans, clients should be advised to contact a physician
Care should be taken to see that the cat consumes the complete dose.
Treated animals should be observed for a few minutes after administrationto ensure that part of the dose is not lost or rejected. If it is suspected that STABILITY: HEARTGARD Chewables for Cats are stable for 3 years when
any of the dose has been lost, redosing with a new chewable is recommended.
stored below 77°F (25˚C) and protected from light. Store at controlled room Fragments of chewables have occasionally been observed in the feces of temperature of 68°F - 77°F (20°C - 25°C). Excursions between 59°F - 86°F (15°C - some cats; efficacy of the product was not adversely affected.
HEARTGARD for Cats should be given at monthly intervals when mosquitoes HOW SUPPLIED: HEARTGARD for Cats is available in two dosage
potentially carrying infective heartworm larvae are active. The initial dose strengths (see DOSAGE section) for cats of different weights. Each strength must be given within a month (30 days) after the cat’s first exposure to comes in a convenient carton of 6 chewables, packed 10 cartons per tray.
mosquitoes. The final dose must be given within a month (30 days) after thecat’s last exposure to mosquitoes. For optimal performance, HEARTGARD for For customer assistance, please contact Merial at 1-888-637-4251.
Cats must be given once a month on or about the same date. If treatment is ®HEARTGARD and the Cat & Hand Logo are registered trademarks of Merial. 2011 Merial Limited, Duluth, GA. All rights reserved.

Source: http://www.heartgard.com/SiteCollectionDocuments/HEARTGARD-Chewables-for-Cats.pdf