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There are a variety of drugs available to treat migraines. You should work carefully with your doctor to decide which one
is best for you.
TRIPTANS
Triptans are the newest and most effective drugs used in the treatment of migraine. They are also the first class of drugs specifically developed for migraine patients, although they are effective against other types of headaches, too. Triptans work by maintaining levels of serotonin, a brain chemical responsible for many functions including vascular constriction, which is thought to be responsible for migraine pain. Triptans are available as oral, nasal and injectible formulas. Examples of triptans include sumatriptan succinate, almotriptan malate, naratriptan hydrochloride, rizatriptan, zolmitriptan, frovatriptan succinate, and eletriptan hydrobromide. Triptans are generally well tolerated, however possible side effects can include a tingling feeling, drowsiness, dizziness, and weakness. Less common side effects include temporary chest pressure or rash. NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)
NSAIDs can be effective for mild-to-moderate headache pain. NSAIDs work by constricting dilated blood vessels, Some NSAID formulations include caffeine. Caffeine is one of history's oldest headache remedies because of its natural ability to constrict blood vessels. Some of the most common over-the-counter NSAID pills are aspirin, ibuprofen, and naproxen. Prescription NSAIDs include oral preparations as well as fast-acting injectables; examples are diclofenac, etodolac, fenoprofen, flurbiprofen, indomethacin, ketoprofen, meloxicam, nabumetone, oxaprozin, piroxicam, sulindac, and tolmetin. The most common side effects of NSAIDs are nausea, vomiting, diarrhea, constipation, decreased appetite, rash, dizziness, headache, and drowsiness. Serious, but uncommon, side effects include kidney failure, liver failure, ulcers, and prolonged bleeding after an injury or surgery. * The information provided is for your education only. By providing this educational service to our community, we are not undertaking to provide you medical advice or treatment. This information does not take the place of, nor is intended to be, a substitute for professional medical advice, diagnosis, or treatment from your doctor. The information does not establish a physician patient relationship or an entitlement to any health services
ERGOTAMINES (ERGOT)
Ergotamines work by constricting smooth muscles, including those in blood vessels. Like NSAIDs, ergotamine formulations can contain caffeine. These drugs can be taken orally, as nasal sprays, or as injections. Examples of ergotamines are dihydroergotamine mesylate and ergotamine tartrate. While ergotamines can help stop a migraine that’s already started, they may also make migraine symptoms, such as nausea and vomiting, worse for some people. Other commonly experienced side effects include dizziness and anxiety. Ergotamines should not be used to treat people who have uncontrolled hypertension, an enlarged prostate, arterial diseases, bowel obstruction, arrhythmia, glaucoma, and heart, liver, or kidney diseases. RESCUE DRUGS
When all else fails, "rescue" drugs can be used to stop a migraine. These should be used only as a last resort, and only with a doctor's supervision. If migraine pain is very severe and does not respond to other drugs, doctors may try opioids. Opioids include morphine, codeine, and oxycodone Care must be taken when using opioids due to the risk of addiction. Side effects of opioids include drowsiness, impaired judgment, nausea, and constipation. CORTICOSTEROIDS
Corticosteroids for migraines are intended strictly for short-term use. Corticosteroids used in the treatment of migraine include methylprednisolone, prednisone, and dexamethasone. Prolonged use of corticosteroids can lead to serious side effects including increased risk of osteoporosis. Additionally, because these drugs can increase blood sugar levels, people with diabetes must be carefully monitored when using corticosteroids. Nursing mothers should avoid corticosteroid use. * The information provided is for your education only. By providing this educational service to our community, we are not undertaking to provide you medical advice or treatment. This information does not take the place of, nor is intended to be, a substitute for professional medical advice, diagnosis, or treatment from your doctor. The information does not establish a physician patient relationship or an entitlement to any health services

Source: http://nvcdn.answerstv.com/AnswersMedia_Health/001_S001_E004Migr_HDITI_Drugs_DrugSummary_BO_PDF.pdf