Schizophrenia dose se charts.pdf

The Antipsychotic Algorithms for treatment of Schizophrenia
Medication Dosing Table
ATYPICAL
Atypical
First Dose
Titration
Schedule
Day 15: 100 mg bidDay 18: 125 mg bidDay 21: 150 mg bidDay 24: 100 mg am 200 mg hs Antipsychotic
Dosages out of range, or of significantly different starting dosages, require an explanation on the Clinical
The Antipsychotic Algorithms for treatment of Schizophrenia Side Effects
Sedation
Anticholinergic
Dysfunction
Side Effects/Co-existing Symptoms
Anti-EPS
Starting Dose
Range
(daily dose)
The Antipsychotic Algorithms for treatment of Schizophrenia
Switching Antipsychotics
Out-patients
1. Institute new antipsychotic at usual rate.
2. Overlap old antipsychotic with new antipsychotic with new antipsychotic by 1-3 weeks, clozapine 3. Consider having patient bring both old and new medications in and set up 7 day pill boxes to get 4. Assess the patient’s ability to follow complicated instructions and enlist family members to help if ***Refer to instructions for Using the Algorithm for detailed explanation of switching drugs.***
Problems Associated with Switching Antipsychotic Agents
Possible decompensation, particularly in early Slow transition, overlap use of typical and stages of treatment (may take > six weeks for atypicals to become effective), with abrupt associated with depression, suicidiality.
Monitor closely.
New side effects; e.g. hypersalivation rather than dry mouth with change to clozapine; weight gain more with clozapine than with some conventional agents that was being given with large doses of discontinuation of high-potency agents.
anticholinergic agent that were not “carried forward.” Withdrawal dyskinesia or akathisia limited, but can be treated by adding back possible whenever typical agent stopped abruptly (dyskinesia especially after abrupt cessation of Possible loss of antipsychotic efficacy.
Depending on anticholinergic effects of previous after a few weeks; if not, consider dosage agent and abruptness of switch, patient may experience either new onset anticholinergic side dietary counseling and increased exercise.
effects or cholinergic rebound symptoms. EPSmay also follow abrupt conversion to high (>5mg/day) doses of risperidone. Weight gain, The Antipsychotic Algorithms for treatment of Schizophrenia
Recommended Doses of Antidepressants
Type/Class
Usual target
Recommended
dose mg/day to
administration
Medication
achieve in weeks 1-3
recommended
schedule
The Antipsychotic Algorithms for treatment of Schizophrenia
Antidepressant/Antipsychotic Interactions
venlafaxine (Effexor) increases haloperidol levels, but not by Cytochrome P450 interaction)
*=Minor pathway

Source: http://www.universityhealthsystem.com/files/11-Antipsychotic%20Medication%20Dosing%20and%20Side%20Effects%20Tables.pdf