Tadalafil gehört zur Gruppe der PDE5-Hemmer und wirkt über eine hochselektive Blockade des Enzyms Phosphodiesterase Typ 5. Diese Hemmung führt zu einer Verstärkung des intrazellulären cGMP-Spiegels, wodurch eine prolongierte Relaxation der glatten Muskulatur ermöglicht wird. Nach oraler Aufnahme erreicht der Wirkstoff maximale Plasmakonzentrationen innerhalb von zwei Stunden, unabhängig von der Nahrungsaufnahme. Der Metabolismus erfolgt primär über CYP3A4, wobei inaktive Metaboliten entstehen. Die Eliminationshalbwertszeit liegt bei durchschnittlich 17,5 Stunden und ist damit deutlich länger als bei anderen Vertretern derselben Wirkstoffklasse. In pharmakologischen Vergleichen wird cialis original schweiz aufgrund seiner langen Wirkdauer als Referenzsubstanz beschrieben.

Layout

G E R A L D W R I G H T : : A R T D I R E C T I O N 212.754.5922 ½ C: 917.312.7334 ½ [email protected] ½ geraldwright.com ½ geraldwrightdesign.com FREELANCE (AUGUST 2006-PRESENT)
Art Supervisor
Clients: DDB, DraftFCB Healthcare, GSW, KPR, Medicus, Sudler & Hennessey
½ Developed launch materials for dermal filler Evolence
½ Created global launch materials for MS drug Avonex
½ Developed concepts for launch of Symbicort asthma medication
½ Created DVD/CD-ROM video and packaging for HIV medication Viracept
½ Developed US branding guidelines book for Zimulti weight loss medication
½ Created convention materials for Sanofi-Aventis Expert Lecture Series
ANDERSON DDB (2004-2006)
Art Supervisor
Clients: Novartis, J&J, Guidant, Cordis, Abbott, Ethicon, Ortho-McNeil, Wyeth
½ Created DTP and DTC advertising campaigns for Guidant, Remicade, Similac and Xolair
½ Managed freelance art directors and agency studio
GERALD WRIGHT DESIGN (2000-2004)
President/Creative Director
Clients: Anderson DDB, A.I.S.T., Non Friction Solutions, Lyons Trail Communications, A.C.E.,
The Music Bank, Pottery-on-Hudson
½ Designed logo and all print materials for A.I.S.T. Symposium HIT2002
½ Created logo and printed materials for Ultra Guard Plus oil additive
GREY NEW YORK (1998-2000)
VP, Associate Creative Director
Clients: Playtex, Wyeth Consumer
½ Created campaigns for Gentle Glide and Silk Glide Tampons to update brand look and appeal
½ Co-developed branding and launch campaign for Centrum Herbal Supplements.
GREY TOKYO (1995-1998)
VP, Creative Director
Clients: P&G, GlaxoSmithKline Consumer, Porsche, Slim Fast
½ Developed copy and shaped campaigns for Pantene that were used as a regional model
½ Created Japanese launch campaign for Oil of Olay, Aquafresh toothpaste and Porsche Japan
½ Trained and supervised local creative teams
GREY TORONTO (1986-1995)
VP, Associate Creative Director
Clients: P&G, GSK Consumer, Bally of Switzerland, Playtex, Slim Fast
½ Led the Canadian creative team that co-developed Pantene’s distinct brand image and
successful launch—making it the #1 shampoo in North America ½ Developed branding and launch for Pantene Elastesse hairspray ½ Broadened Canadian consumer base for Pantene by creating first-ever male TV spot for brand AWARDS: Regional US, Canadian, P&G ‘World Class Advertising”
EDUCATION: B.A. - Fine Arts, Layton School of Art, Milwaukee WI
G E R A L D W R I G H T : : A R T D I R E C T I O N 212.754.5922 ½ C: 917.312.7334 ½ [email protected] ½ geraldwright.com ½ geraldwrightdesign.com CATEGORY & BRAND EXPERIENCE
½ Allergic Rhinitis: Dulera
½ Antibiotic: Doribax
½ Antidepressant: Pristiq
½ Asthma: Xolair, Pulmicort Respules, Symbicort
½ Cardiology: Cypher, Guidant, Integrilin, Multaq
½ Cholesterol: Welchol
½ Colitis: Asacol
½ Dermal filler: Evolence
½ Diabetes: Galvus, Regranex
½ Emphysema (COPD): Spiriva
½ HIV: Viracept
½ Infant nutritional: Similac
½ MS: Avonex
½ Narcolepsy: Xyrem
½ RA/Biologic: Remicade, Simponi
½ Schizophrenia: Invega
½ Tissue adhesive: Dermabond
½ Weight control: Zimulti

Source: http://ad-lib-intl.com/images/Gerald_Wright_Resume.pdf