Tadalafil gehört zur Gruppe der PDE5-Hemmer und wirkt über eine hochselektive Blockade des Enzyms Phosphodiesterase Typ 5. Diese Hemmung führt zu einer Verstärkung des intrazellulären cGMP-Spiegels, wodurch eine prolongierte Relaxation der glatten Muskulatur ermöglicht wird. Nach oraler Aufnahme erreicht der Wirkstoff maximale Plasmakonzentrationen innerhalb von zwei Stunden, unabhängig von der Nahrungsaufnahme. Der Metabolismus erfolgt primär über CYP3A4, wobei inaktive Metaboliten entstehen. Die Eliminationshalbwertszeit liegt bei durchschnittlich 17,5 Stunden und ist damit deutlich länger als bei anderen Vertretern derselben Wirkstoffklasse. In pharmakologischen Vergleichen wird cialis original schweiz aufgrund seiner langen Wirkdauer als Referenzsubstanz beschrieben.

Sterling magazine no. 13

Sterling Fleet
The newest aircraft are
equipped with wing lets,
Forholdsregler i forbindelse med flyvning which saves 4% fuel and
the environment.
Number Engine
Cruising
Max. airline
Max. passengers
Length, Wing Height, Max.
range, cruising passen- m
take-off
craftedsmæssigt en meget sikker
height, mlangt
gers de fleste passager
weight, kg
påvirkninger, som kroppen udsættes for under flyvning. Boeing 737-800 10
CFM 56-7B26 850
5,500 12,500
34.4 12.5
Når man sidder stille i en længere periode uden at bevæge benene, kan dette medføre en – for langt Boeing 737-700 lille
9 risiko for
CFat udvikle dyb
M 56-7B22
12,500 på dansk
33.6 blodprop
34.4 i benene.
Boeing 737-500 6
CFM 56-3C-1 805
3,500 11,250
28.9 11.2
On the whole, flying is a very safe form of transport, and most passengers can tolerate the factors to which the body is exposed during a flight. Sitting still for a fairly long period of time without moving your legs may cause a risk that for most pas- deep vein thrombosis (DVT) or in English, blood clots in the legs. Forslag til lp y
forebyggelse af
blodpropper i
Ways of preventing deep-vein thrombosis
Da Maersk Air ønsker, at flyveturen skal være e e Maersk Air wants flying to be a positive experience for all our oplevelse for alle vores passagerer, anbefaler vores lægelige 1 Vær forberedt til flyveturen, mød op i god tid og undgå
1 Be well-prepared for your trip, arrive in good time and avoid
On the whole, fl
med vand y safe
form of tr
Undgå or
er, and mo
dreven st pas-
sengers can toler
for samt ate the
factors to
which the b
fødder os
4 Keep moving your feet and legs frequently during the flight
2 Drink plenty of water before and
d for 9 If you have any doubts or con-
a fl ight
5 .Udfør hyppige skift af siddestilling, d
undersiden af låret hele tiden ændr 3 A
Sitting still for a fairly long period of blodet fra benene uhindret vil kunne coff e We hope that you
6 Wearing support hose during the flight is
enj recommended
oy your fl ight. for
4 Keep moving your feet and
M vascular
ads Klok condi-
7 A junior a
enior Physician and
afrejsedagen, såfremt dette tåles, og fl igh ekommer culation. 7 A acetyl salic
Steff acid)
en L is recom-
Ways of preventi
sygdom, ep-vei
mended on the day you travel, if you can S tolerate
enior Phyit and
sician are
8 Såfremt De bruger medicin,
thrombosis Sterling wants fl ying to
Medical Department Flight
Operations.
9 sitive e
tvivl erience for a
anbefales det ll ou
flyvning- t the 8 If not suff
passengers
en. . Our medical depart-
Sterling
ment has compiled the following
9 If you have any doubts or concerns, consult
enhag own doctor
en Airport South
DK-2791 Dragør

Source: http://adventure.dk/sterling/13/singles/082.pdf