Material Safety Data Sheet
Section 1: Chemical Product and Company Identification
14025 Smith Rd.
US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
TSCA 8(b) inventory: No products were found.
CHEMTREC (24HR Emergency Telephone), call:
Clotrimazol, Chlotrimazole Lotrimin,
Mycelex, Mycelax; (Chlorotrityl)imidazole; 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole; 1-
International CHEMTREC, call:
For non-emergency assistance, call:
Section 2: Composition and Information on Ingredients
% by Weight
Toxicological Data on Ingredients:
Clotrimazole: ORAL (LD50): Acute: 708 mg/kg [Rat]. 761 mg/kg [Mouse]. 750 mg/kg
Section 3: Hazards Identification
Potential Acute Health Effects:
Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of
Potential Chronic Health Effects:
Slightly hazardous in case of skin contact (sensitizer). CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS:
Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available.
Section 4: First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious
person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar,
tie, belt or waistband.
Section 5: Fire and Explosion Data
Flammability of the Product:
May be combustible at high temperature.
Products of Combustion:
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.), halogenated
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards:
Special Remarks on Explosion Hazards:
Section 6: Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on
the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the
contaminated surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not
breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Section 8: Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
Section 9: Physical and Chemical Properties
Physical state and appearance:
Solid. (Solid crystalline powder.)
White to yellowish. (Light.)
pH (1% soln/water):
Water/Oil Dist. Coeff.:
Ionicity (in Water):
See solubility in water, acetone.
Soluble in acetone. Very slightly soluble in cold water, diethyl ether.
Section 10: Stability and Reactivity Data
The product is stable.
Conditions of Instability:
Excess heat, dust generation.
Incompatibility with various substances:
Non-corrosive in presence of glass.
Special Remarks on Reactivity:
Special Remarks on Corrosivity:
Will not occur.
Section 11: Toxicological Information
Routes of Entry:
Toxicity to Animals:
Acute oral toxicity (LD50): 708 mg/kg [Rat].
Chronic Effects on Humans:
Other Toxic Effects on Humans:
Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals:
Lethal Dose Conc/50% Kill: LD50 [Rabbit] - Route: Oral; Dose: >1000 mg/kg LD50 [Dog] - Route: Oral; Dose: >2000 mg/kg
LD50 [Cat] - Route: Oral; Dose: >1000 mg/kg
Special Remarks on Chronic Effects on Humans:
May cause adverse reproductive effects (Maternal effects - cervix, uterus, ovaries, fallopian tubes, and effects on fertility -
fetotoxicity, and post-implantation mortality
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Topical or oral overdose with this material is not expected to be life threatening. Skin:
May cause skin irritation. May cause stinging, blistering, peeling, edema, pruritus, urtiaria, burning sensation. Eyes: May
cause eye irritation. Inhalation: May cause respiratory tract irritation. Ingestion: May be harmful if swallowed. May cause
gastrointestinal tract irritation with nausea, vomiting, diarrhea, abdominal cramping or pain. Although it is poorly absorbed
from the gastrointestinal tract, it may affect behavior (somnolence, muscle weakness, convulsions). Chronic Potential Health
Effects: Possible allergic reaction to material if inhaled, ingested or in contact with skin. Although it is poorly absorbed from the
gastrointestinal tract, chronic ingestion may also affect liver, urinary tract and blood
Section 12: Ecological Information
BOD5 and COD:
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation:
The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation:
Section 13: Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
Not a DOT controlled material (United States).
Special Provisions for Transport:
Section 15: Other Regulatory Information
Federal and State Regulations:
No products were found.
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Not controlled under WHMIS (Canada).
R22- Harmful if swallowed. S2- Keep out of the reach of children. S46- If swallowed, seek medical advice immediately and
show this container or label.
National Fire Protection Association (U.S.A.):
Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles.
Section 16: Other Information
Other Special Considerations:
10/09/2005 04:57 PM
11/06/2008 12:00 PM
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INTEGRATING MICROARRAY AND PROTEOMICS DATAANNELEEN DAEMEN1 ∗ , OLIVIER GEVAERT1, TIJL DE BIE2, ANNELIESDEBUCQUOY3, JEAN-PASCAL MACHIELS4, BART DE MOOR1 AND1 Katholieke Universiteit Leuven, Department of Electrical Engineering (ESAT), SCD-SISTA (BIOI), Kasteelpark Arenberg 10 - bus 2446, 2 University of Bristol, Department of Engineering Mathematics, Queen’s Building, University Walk, B
L’ANTICONCEPCIÓ D’EMERGÈNCIA AMB LEVONORGESTREL A LES OFICINES DE FARMÀCIA DISPENSACIÓ SENSE PRESCRIPCIÓ MÈDICA Generalitat de Catalunya Departament de Salut L’ANTICONCEPCIÓ D’EMERGÈNCIA AMB LEVONORGESTREL A LES OFICINES DE FARMÀCIA 1. Introducció 2. Indicació de l’anticoncepció d’emergència 3. Accés a l’anticoncepció d’emergència 4. Pr