duce large amounts of insulin. So, while they
feel tired and too lightheaded to complete your
cising at noon or after work even though you’re
may give you an initial boost, your energy will
truly committed to exercise and it’s the only time
drop off quickly, and your mood will follow.
If you plan to engage in running or other high-
The amount of sugar in your blood is also
ly vigorous activity, remember that some forms of
Do you feel so exhausted that you just can’t
related to the amount of serotonin in your brain.
caffeine, coffee in particular, can lead to mild gas-
Serotonin is an important chemical called a neu-
tronomical distress, as can some bulky foods. So,
Your diet—rather than simple sloth—may be
rotransmitter that helps to regulate mood. If your
you’d be wise to limit the amount of coffee, tea
the problem. If you tend to skip meals in an
level of serotonin is where it should be, you’ll have
and soda that you drink for a number of reasons.
attempt to save calories, you may be robbing your-
a sense of well-being and confidence—and feel
Suppose you’re an early bird, and your best
self of important fuel for your workout. While
ready to tackle the treadmill. Should it drop, you
time to work out is in the morning before you go
skipping meals may temporarily make your stom-
may feel tired and depressed. If you often experi-
to work. For quick energy, drink some juice upon
ach feel flatter, doing so can also leave you feeling
ence a craving for carbs, this may be your brain’s
rising and avoid coffee. Once you’ve completed
tired, irritable and unfocused. Then, you’ll be
way of telling you it needs more serotonin.
your workout, have a more solid breakfast of
tempted to forego your noontime workout, or go
whole-wheat cereal or toast and fruit to fuel your
home, eat and stretch out on the couch in front of
concentration for the morning’s work. If you work
You’ll keep your motivation
out and eat too lightly, chances are you’ll get “the
to exercise if you:
If, however, you follow some simple, sensible
drowsies” by 2 p.m., if not sooner.
• Have a glass of juice to boost your energy
dietary practices throughout your day, you’ll get
Keep in mind that finding the right combina-
tion of food and drink to energize your work-
that workout done. And rather than feeling light-
• Eat a breakfast that includes whole grains
out—whatever time of day you choose—may take
headed and exhausted afterward, you’ll be ener-
some experimenting. It all depends upon your
• Eat small, frequent small meals and snacks
individual tastes and your metabolism. With a little
during the day to maintain your blood sugar.
patience, an open mind and a little creativity, you’ll
One key to staying motivated to exercise is to
• Make sure to have a light, healthy snack an
keep the amount of sugar in your blood—and
hour before your noon or after-work workout.
thus, your energy level—stable to prevent ups and
• Stay hydrated, keeping a water bottle at your
downs. You can best do that by eating a series of
small meals throughout the day—as many as fiveor six—that are composed of complex carbohy-
• Limit—or eliminate—the amount of caffeine
drates, such as whole grain breads, beans and
other vegetables, whole grain crackers and fruit. If
you plan ahead and make time for grocery shop-
ping, you can easily pack some simple meals and
What about caffeine? Good question. Many ath-
letes rely on caffeine for the initial kick it can pro-
your blood sugar stable because they are digest-
vide. Remember, though, that caffeine can also
ed and absorbed slowly into the blood and
affect the amount of insulin, and thus, sugar, in
don’t require your pancreas to produce much
your blood. Further, it can cause dehydration,
insulin. Refined carbohydrates, such as potato
While drinking a caffeinated beverage may
chips, doughnuts and cookies, are absorbed
help get you to the gym, within an hour you may
very quickly and trigger the pancreas to pro-
If you are interested in information on other health and fitness topics, contact: American Council on Exercise, 4851 Paramount Drive, San Diego, CA 92123, 800-825-3636; or, go online at http://www.acefitness.org and access the complete list of ACE Fit Facts.
Original Paper Accepted: August 6, 2008 Published online: September 17, 2008 Chemoembolization Combined with Pravastatin Improves Survival in Patients with Hepatocellular Carcinoma Hannah Graf a Christoph Jüngst g Gundula Straub a Selin Dogan f Ralf-Thorsten Hoffmann b Tobias Jakobs b Maximilian Reiser b Tobias Waggershauser b Thomas Helmberger d Andreas Walter e Autar Walli c D
Pharmacokinetic Study of Bupropion Hydrochloride Products with Different Release Patt. Page 1 of 3 Pharmacokinetic Study of Bupropion Hydrochloride Products with Different Release Patterns Solicitation Number: 1116087 Agency: Department of Health and Human Services Office: Food and Drug Administration Location: Office of Acquisitions and Grants Services Notice Type: Posted Date: