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International Journal of Global Research in Science and Technology, Vol. 1, Issue 1 Published by YCIS, Satara, Maharashtra, India CONVERSION OF 3-FORMYL CHROMONE IN TO BIOLOGICALLY
IMPORTANT HETEROCYCLIC COMPOUNDS.
A S Burungalea, B K Karale*b
a=Yashawantrao Chavan Institute of Science, Satara, Maharashtra. *b=P G Dept. of Chemistry, Radhabai Kale Mahila Mahavidyalaya, Ahmednagar, Abstract: 3-Formyl chromone 1 when
yl)acetic acid in dry pyridine afforded the compound 3-(2-benzo[d]isoxazol-3- yl-vinyl)-chromon-4-one 2. Compound 2
on treatment with hydrazine hydrate chlorochromones13 reported by us earlier pyrazol-3-yl)phenol 3.
three electron deficient sites viz. C-2, Alzheimer’s type (SDTA) results from a International Journal of Global Research in Science and Technology, Vol. 1, Issue 1 Published by YCIS, Satara, Maharashtra, India alleviate memory deficit in patients with found to be associated with antiviral24, antitumor25, 26 and antifungal activities. found wide use as antibiotics, sedatives, fact, the 1,2-benisoxazoles, a large class activities of pyrazoles, benzoisoxazole, therapeutic agents23. Fluorinated analogs International Journal of Global Research in Science and Technology, Vol. 1, Issue 1 Published by YCIS, Satara, Maharashtra, India Chromone 2 on treatment with
chromone 1 when heated with 2-
(benzo[d]isoxazol-3-yl)acetic acid in dry opening and affords compound 3.
Compound 3 shows characteristic IR
4-one 2. Compound 2 on heating with
structure of compounds 3 are also
(4-((E)-2-(benzo[d]isoxazol-3-yl)vinyl)- 1H-pyrazol-3-yl)phenol 3.
Result and Discussion
SCHEME:-1
Experimental Section
International Journal of Global Research in Science and Technology, Vol. 1, Issue 1 Published by YCIS, Satara, Maharashtra, India Chromone 2 (0.001 mole) and 1 ml of
temperature and poured into crushed ice, standard (chemical shifts in  values). thus obtained was separated by filtration method are listed in Table I. 3b: IR:
spectra and elemental analysis. Purity of & 10.1 (s, 1H, exchangeable with D2O). Mass: 3b: M+ 337.
2-(4-((E)-2-(Benzo[d]isoxazol-3-
yl)vinyl)-1H-pyrazol-3-yl)phenol 3a-
Table I- Characterization data of the synthesized compounds.
International Journal of Global Research in Science and Technology, Vol. 1, Issue 1 Published by YCIS, Satara, Maharashtra, India References
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Caffeine’s Effect on Appraisal and Mental Arithmetic Performance: A Cognitive Modeling Approach Tells Us More Sue E. Kase (skase@ist.psu.edu), Frank E. Ritter (frank.ritter@psu.edu) College of Information Sciences and Technology, Pennsylvania State University Michael Schoelles (schoem@rpi.edu) Cognitive Science Department, Rensselaer Polytechnic Institute Abstract observati

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