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SUBJECT: Cytotoxic Drug Permeation testing of KIMTECH* gloves
Dear Valued Customer,
Thank you for your enquiry about our gloves and their use for protection against chemical splash hazards by
cytotoxic drugs.
We must caution that the selection of the most appropriate glove for a specific task should be carried out by a
trained safety professional following a ful risk assessment. It is Kimberly- Clark’s intent to provide data which
can enable trained professionals to make an informed choice.
This letter contains the results of chemical permeation testing of cytotoxic drugs, performed on the fol owing gloves only: KIMTECH PURE* G3 Sterile White Nitrile gloves KIMTECH PURE* G3 Sterile STERLING* NITRILE gloves KIMTECH PURE* G3 STERLING* NITRILE gloves KIMTECH PURE* G5 STERLING* NITRILE gloves KIMTECH SCIENCE* STERLING* NITRILE gloves and STERLING* NITRILE-XTRA gloves KIMTECH SCIENCE* PURPLE NITRILE* gloves and PURPLE NITRILE-XTRA* gloves. The fol owing test standards are referenced in this letter: - EN374-3:2003 (Protective gloves against chemicals and micro-organisms; Part 3: Test for determination of resistance to permeation by chemicals) - ASTM D 6978-05 (Standard practice for assessment of resistance of medical gloves to permeation by KIMTECH PURE* G3 Sterile White Nitrile gloves were tested according to EN374-3:2003, adapted with a reduction in swatch area chamber size, making it possible to use much smal er amounts of the toxic donor solution compared to the standard method. Results: Drug and Concentration
Tests were carried out by an independent laboratory, under laboratory test conditions. These tests may not adequately replicate any specific condition of use, and because KIMBERLY-CLARK has no detailed knowledge or control over the conditions of end use, any of these data must be advisory only, and KIMBERLY-CLARK must decline any liability. KIMTECH PURE* G3 Sterile STERLING* NITRILE gloves were tested according to ASTM D 6978-05 Standard Test Method for Resistance of Protective Clothing materials to Permeation by Liquids or Gases under Conditions of Continuous Contact. Results: Drug and Concentration
Breakthrough time
Tests were carried out by an independent laboratory, under laboratory test conditions. These tests may not adequately replicate any specific condition of use, and because KIMBERLY-CLARK has no detailed knowledge or control over the conditions of end use, any of these data must be advisory only, and KIMBERLY-CLARK must decline any liability. Warning: Do not use this glove when there is a risk of exposure to splash hazards by Carmustine and Thiotepa. KIMTECH PURE* G3 STERLING* NITRILE gloves, KIMTECH PURE* G5 STERLING* NITRILE gloves, KIMTECH SCIENCE* STERLING* NITRILE gloves and KIMTECH SCIENCE* STERLING* NITRILE-XTRA gloves, are made from the same formulation, processing techniques as KIMBERLY-CLARK* STERLING* Nitrile gloves, were tested according to ASTM D 6978-05. Results: Drug and Concentration
Breakthrough time
Tests were carried out by an independent laboratory, under laboratory test conditions. These tests may not adequately replicate any specific condition of use, and because KIMBERLY-CLARK has no detailed knowledge or control over the conditions of end use, any of these data must be advisory only, and KIMBERLY-CLARK must decline any liability. Warning: Do not use this glove when there is a risk of exposure to splash hazards by Carmustine and Thiotepa. KIMTECH SCIENCE* PURPLE NITRILE* gloves and KIMTECH SCIENCE* PURPLE NITRILE-XTRA* gloves, are made from the same formulation, processing techniques as KIMBERLY-CLARK* PURPLE NITRILE* gloves, were tested according to ASTM D 6978-05. Results: Drug and Concentration
Breakthrough time
Tests were carried out by an independent laboratory, under laboratory test conditions. These tests may not adequately replicate any specific condition of use, and because KIMBERLY-CLARK has no detailed knowledge or control over the conditions of end use, any of these data must be advisory only, and KIMBERLY-CLARK must decline any liability. Warning: Do not use this glove when there is a risk of exposure to splash hazards by Carmustine and Thiotepa. We hope this information has been helpful. If we can assist further please let us know at infofax@kcc.com Regards Jaime Cassar KIMBERLY-CLARK Category Manager EMEA - KIMTECH*

Source: http://www.kimtech.eu/media/2021/Cytotoxic%20Drug%20Testing.pdf

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