Effects of cGMP-dependent protein kinase and calmodulin on
8 Suematsu, E., Hirata, M. and Kuriyama, H. Ca2+ uptake by highly purified sarcolemmal vesicles of vascular Biochim. Biophys. Acta 773,
Biochem. Biophys. Res. Commun. 120,
1 Suematsu, E., Hirata, M., Hashimoto, T. and Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular
store sites in skinned single cells of porcine coronary artery.
Release of Ca2+ from a non-mitochondrial store site in
3 Hirata, M., Suematsu, E., Hashimoto, T.,
Biochem. J. 223,
peritoneal macrophages treated with saponin by inositol 1,4,5-trisphosphate.
A role for inositol 1,4,5-trisphosphate in the initiation of
6 Hashimoto, T., Hirata, M. and Ito, Y.
Br. J. Pharmacol. 86,
agonist-induced contractions of dog tracheal smooth muscle.
Dependence on Ca2+ of the activities of phosphatidylinositol
7 Sasaguri, T., Hirata, M. and Kuriyama, H. 4,5-bisphosphate phosphodiesterase and inositol 1,4,5-
Biochem. J. 231,
trisphosphate phosphatase in smooth muscles of the porcinecoronary artery.
Irreversible inhibition of Ca2+ release in saponin-treated
Hashimoto, T. Kukita, M. and Koga, T.
macrophages by the photoaffinity derivative of inositol 1,4,5-trisphosphate.
Inositol 1,4,5- trisphosphate activates pharmacomechanical
2 Hashimoto, T., Hirata, M., Itoh, T., Kanmura,
coupling in smooth muscle of the rabbit mesenteric artery.
Guanine nucleotide binding protein involved in muscarinic
Sasaguri, T., Hirata, M., Koga, T., Itoh, T. and
responses in the pig coronary artery is insensitive to islet-
Calmodulin activates inositol 1,4,5-trisphosphate 3-kinase
Yamaguchi, K., Hirata, M. and Kuriyama, H.
Biochem. J. 244,
activity in pig aortic smooth muscle.
Stimulatory effects of atrial natriuretic factor on
Biochim. Biophys. Acta 1010,
5 Hirata, M., Chang, C.-H. and Murad, F.
phosphoinositide hydrolysis in cultured bovine aortic smooth
Synthetic inositol trisphosphate analogs and their effects on
10 Hirata, M., Watanabe, Y., Ishimatsu, T., Ikebe,
T., Kimura, Y., Yamaguchi, K., Ozaki, S. and
J. Biol. Chem. 264,
phosphatase, kinase, and the release of Ca2+.
Mechanism of cyclic GMP inhibition of inositol phosphate
4 Hirata, M., Kohse, K.P., Chang, C.-H., Ikebe, formation in rat aorta segments and cultured bovine aortic J. Biol. Chem
Chang, C.-H., Kohse, K.P., Chang, B., Hirata, Characterization of ATP-stimulated guanylate cyclase
Biochim. Biophys. Acta 1052,
M., Jiang, B., Douglas, J.E. and Murad, F.
Inositol 1,4,5-trisphosphate affinity chromatography.
Biochem. Biophys. Res. Commun
Hirata, M., Yanaga, F., Koga, T., Ogasawara, Stereospecific recognition of inositol 1,4,5-trisphosphayte
J. Biol. Chem. 265,
analogs by the phosphatase, kinase, and binding proteins.
Signal transduction by tumor necrosis factora is mediated
Yanaga, F., Abe, M., Koga, T. and Hirata, M. through a guanine nucleotide binding protein in osteoblast-like J. Biol. Chem. 267,
Putative inositol 1,4,5-trisphosphate binding proteins in rat
Ozaki, S., Yoshida, M., Koga, T., Iwanaga, S.
J. Biol. Chem. 267,
and Hirata, M.
Sasaguri, T., Kosaka, C., Hirata, M., Masuda, Protein kinase C-mediated inhibition of vascular smooth
J., Shimokado, K., Fujishima, M. and Ogata, muscle cell proliferation:The isoforms that may mediate G1/S Exp. Cell Res
Dexamethasone stimulates osteoclast-like cell formation by
Shuto, T., Kukita, T., Hirata, M., Jimi, E. and
inhibiting granulocyte-macrophage colony-stimulating factor
production in mouse bone marrow cultures.
Expression and characterization of an inositol 1,4,5-
9 Yagisawa, H., Hirata, M., Kanematsu, T.,
Watanabe, Y., Ozaki, S., Sakuma, K., Tanaka, trisphosphate binding domain of phosphatidylinositol-specific J. Biol. Chem
H., Yabuta, N., Kamata, H., Hirata, H. and
A new inositol 1,4,5-trisphosphate binding protein similar to
Ozaki, S., Koga, T., Iwanaga, S., Ikehara, Y.
Biochem. J. 313,
Jimi, E., Ikebe, T., Takahashi, N., Hirata, M., Interleukin-1α activates an NF-κB-like factor in osteoclast-like
J. Biol. Chem. 271,
Distinct specificity in the binding of inositol phosphates by
Biochim Biophys. Acta 1359,
pleckstrin homology domains of pleckstrin, RAC-protein
Watanabe, Y., Katan, M. and Hirata, M.
kinase, diacylglycerol kinase and a new 130-kDa protein.
Replacements of single basic amino acids in the pleckstrin
Yagisawa, H., Sakuma, K., Paterson, H.F.,
homology domain of phospholipase C-δ1 alter the ligand
Cheung, R., Allen, V., Hirata, H., Watanabe,
J. Biol. Chem. 273,
binding, phospholipase activity and interaction with the plasma
Y., Hirata, M., Williams, R.L. and Matilda, K. membrane.
Hermosura, M.C., Takeuchi, H., Fleig, A.,
Riley, A.M., Potter, B.V.L., Hirata, M. and
4 facilitates store-operated calcium influx by inhibition of
VIII. A Compound by Any Other Name Is . . . A Different Compound!!! 1. A long time ago we talked about Dalton’s Law of Multiple Proportions which said that you could get different compounds from the same elements by changing the ratios of atoms of the elements. For example, you could have C1O1 (although the 1’s are normally not written) and C1O2 . As a result of the fact that t
Animal Aid Factfile Focus on Fish Background the process and also to adopt a truly consistentstance by ending fish sales as well. In June 2003,In the mid 1990’s, DIY giant Focus Do it All begunthe firm’s commercial director wrote to Animalselling a range of ‘pet’ animals in its stores, Aid confirming that Focus were now committedincluding small mammals, reptiles, fish and