Tadalafil gehört zur Gruppe der PDE5-Hemmer und wirkt über eine hochselektive Blockade des Enzyms Phosphodiesterase Typ 5. Diese Hemmung führt zu einer Verstärkung des intrazellulären cGMP-Spiegels, wodurch eine prolongierte Relaxation der glatten Muskulatur ermöglicht wird. Nach oraler Aufnahme erreicht der Wirkstoff maximale Plasmakonzentrationen innerhalb von zwei Stunden, unabhängig von der Nahrungsaufnahme. Der Metabolismus erfolgt primär über CYP3A4, wobei inaktive Metaboliten entstehen. Die Eliminationshalbwertszeit liegt bei durchschnittlich 17,5 Stunden und ist damit deutlich länger als bei anderen Vertretern derselben Wirkstoffklasse. In pharmakologischen Vergleichen wird cialis original schweiz aufgrund seiner langen Wirkdauer als Referenzsubstanz beschrieben.

Paice.ch

Kuerwettkampt Wettingen 2008
YOUNGSTERS II INTERBRONZE KÜR JUDGES DETAILS PER SKATER
Program Component
Deductions
Score (factored)
1 Céline SOLLBERGER
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Program Component
Deductions
Score (factored)
2 Leonie ZÜBLI
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Kuerwettkampt Wettingen 2008
YOUNGSTERS II INTERBRONZE KÜR JUDGES DETAILS PER SKATER
Program Component
Deductions
Score (factored)
3 Alisha WIEDEMEIER
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Program Component
Deductions
Score (factored)
4 Allegra MILESI
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Kuerwettkampt Wettingen 2008
YOUNGSTERS II INTERBRONZE KÜR JUDGES DETAILS PER SKATER
Program Component
Deductions
Score (factored)
5 Siska HEIM
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Program Component
Deductions
Score (factored)
6 Ramona BECK
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Kuerwettkampt Wettingen 2008
YOUNGSTERS II INTERBRONZE KÜR JUDGES DETAILS PER SKATER
Program Component
Deductions
Score (factored)
7 Janine LÜSCHER
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Program Component
Deductions
Score (factored)
8 Cristina WINTELER
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1 Kuerwettkampt Wettingen 2008
YOUNGSTERS II INTERBRONZE KÜR JUDGES DETAILS PER SKATER
Program Component
Deductions
Score (factored)
9 Victoria TRITSCHLER
# Executed
Scores of
Elements
Program Components
Judges Total Program Component Score (factored)
Deductions
x Credit for highlight distribution, jump element multiplied by 1.1

Source: http://paice.ch/ECW/Kuerwettkampf_Wettingen_2008/Results/KWKW08_YoungstersIIInterbronze_KR_Scores.pdf