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Papers


Book Chapters

1. Saunders G, McFadden J. Molecular Biology of Mycobacterium
tuberculosis. In: Kaufmann SH, Hahn H, editors. Mycobacteria and TB. Basel: S. Karger, 2003. 2. Sheridan, G. and McFadden, J. (2002) Molecular biology of
Mycobacterium tuberculosis. In: Mycobacteria and TB. Ed. Stefan Kaufmann and Helmut Hahn. Karger AG, Basel. 3. Stewart GS and McFadden, J. (1999) Recombination (in
mycobacteria). Mycobacteria: Molecular Biology and Virulence. Edited by C. Ratledge and J W. Dale, Oxford:Blackwell, 1999, p. 1-16. 4. Fidler, H. and McFadden, J. (1997). Mycobacteria and Crohn's
disease. In Inflammatory Bowel Disease. R. Allen, J.Jm. Rhodes, and S.B. Hanauer, eds. (London: Churchill Livingstone), pp. 125-131. 5. McFadden, J. and Stoker, N.G. (1996). Mycobacteria. In Encyclopedia
of Molecular Biology and Molecular Medicine. R.A. Mayers, ed. (Weinheim: VCH), pp. 156-165. 6. McFadden, J. and Stoker, N. (1995). Mycobacteria. In Molecular
Biology and Biotechnology. A comprehensive Desk Manual. R.A. Meyers, ed. (New York: VCH Publishers, Inc.), pp. 582-585. 7. McFadden, J. and Fidler, H. (1995). Mycobacteria and Crohn's
disease. In Inflammatory Bowel Disease. G.N.J. Tytgat, J.F.W.M. Bartelsman, and S.J.H. van Deventer, eds. (Dordrecht: Kluwer Academic Publishers), pp. 451-458. 8. Dale, J.W., Dellagostin, O.A., Norman, E., Barrett, A.D.T., and
McFadden, J. (1993). Multivalent BCG vaccines. In Novel delivery
systems for oral vaccines. D.T. O'Hagan, ed. (Boca Raton: CRC Press),
9. McFadden, J.J. (1992). Mycobacteria. In Encyclopedia of Microbiology.
J. Lederberg, ed. (San Diego: Academic Press), 10. McFadden, J.J. and Seechurn, P. (1992). Mycobacteria and Crohn's
disease. Molecular approaches. In Inflammatory Bowel Disease. R. Macdermott and W. Stenson, eds. (New York: Elsevier Press), pp. 259-271. 11. McFadden, J.J. (1991). Principles of nucleic acid hybridization. In
Methods in Gene Technology. P.G. Sanders and J.W. Dale, eds. (London: JAI Press), pp. 1-14. 12. McFadden, J.J. and Knight, A. (1991). DNA probes for the detection
and identification of bacteria. In Genetic Manipulation. Techniques and Applications. J.M. Grange, A. Fox, and N.L. Morgan, eds. (Oxford: Blackwell Scientific), pp. 97-111. 13. McFadden, J.J., Kunze, Z., and Seechurn, P. (1990). DNA probes
for detection and identification. In Molecular Biology of the Mycobacteria. J.J. McFadden, ed. (Surrey University Press), pp. 139-172. 14. McFadden, J.J., Thompson, J., Hull, E., Hampson, S., Stanford, J.,
and Hermon-Taylor, J. (1988). The use of cloned DNA probes to
examine organisms isolated from Crohn's disease tissue. In
Inflammatory Bowel Disease: R.P. MacDermott, ed. (Elsevier), pp. 515-
520.
1. McFadden, J. (1996). Recombination in mycobacteria. Molecular
Microbiology 21, 205-211.
2. McFadden, J. and Sajduda, A. (1996). Application of molecular
methods to the epidemiology of tuberculosis and other
mycobacterioses. Medical Microbiology Letters 5, 394-399.
3. McFadden, J.J. (1993). Molecular Biology of the Mycobacteria.
Annal.Biol.Clin. 51, 3-5.
4. McFadden, J.J., Kunze, Z.M., Portaels, F., Labrousse, V., and
Rastogi, N. (1992). Epidemiological and genetic markers, virulence
factors and intracellulare growth of Mycobacterium avium in AIDS.
Research Microbiol. 143, 423-436.
5. Rastogi, N., McFadden, J.J., Ottenhoff, T.H.M., and van Eden, W.
(1992). First international conference on the pathogenesis of
mycobacterial infections: A summary. Clin.Infec.Dis. 14, 308-312.
6. Green, E.P., Moss, M.T., Hermon-Taylor, J., and McFadden, J.J.
(1989). Insertion elements in Mycobacteria. Acta Leprologica 7, 239-
242.
Research Papers
1. McFadden JJ. The Conscious Electromagnetic Information (Cemi)
Field Theory:The Hard Problem Made Easy? Journal of Consciousness Studies 2002; 9. 2. McFadden J. Synchronous firing and its influence on the brain's
electromagnetic field: evidence for an electromagnetic theory of consciousness. Journal of Consciousness Studies 2002; 9(4):23-50. 3. Medeiros MA, Dellagostin OA, Armoa GR, Degrave WM, De
Mendonca L, Lopes MQ et al. Comparative evaluation of
Mycobacterium vaccae as a surrogate cloning host for use in the study of
mycobacterial genetics. Microbiology 2002; 148(Pt 7):1999-2009.
4. F. W. da Cruz, A. J. A. McBride, F. R. Conceicao, J. McFadden, and
O. A. Dellagostin (2002). Expression of the B-cell and T-cell epitopes of
the rabies virus nucleoprotein in Mycobacterium bovis BCG and
induction of a humoral response in mice. Vaccine 20:731-736.
5. M. Boruä, A. Sajduda, I. Pawéowska, J. J. McFadden, and J.
Dziadek (2001). Detection of Mycobacterium tuberculosis in clinical
samples using insertion sequences IS 6110 and IS990. Tuberculosis
(Edinb) 81 (4):271-278, 2001.
6. Johnson, C.R., Newcombe, J., Borde, H.A., Gorringe, A.R.,
Funnell, S.G.P., and McFadden, J. (2001). Characterisation of a phoP
mutant of Neisseria meningitidis. Mol.Microbiol. 39: 1345-1355.
7. McFadden, J. and Al-Khalili, J. (2001) Comment on Book Review of
`Quantum Evolution' (Johnjoe McFadden) by Mathew J. Donald. Quantum Physics, archive: The Quantum Physics e-print Archive at http://xxx.lanl.gov/archive/quant-ph: quant-ph/0110083. 8. Stewart, G.S., Ehrt, S., Riley, L.W., Dale, J.W., and McFadden, J.
(2000). Allelic replacement of the antioxidant gene noxR1 in M. bovis
BCG. Tubercle and Lung Disease, 80: 237-242.
9. Ghanekar, K., McBride, A., Dellagostin, O.A., Mooney, R., and
McFadden, J.J. (1999). Stimulation of transposition of the
Mycobacterium tuberculosis insertion sequence IS 6110 by exposure to
a microaerobic environment. Mol.Microbiol. 33, 982-993.
10. McFadden, J. and Al-Khalili, J. (1999). A quantum mechanical model
of adaptive mutation. Biosystems 50, 203-211.
11. Wall, S., Ghanekar, K., McFadden, J., and Dale, J.W. (1999).
Context-sensitive transposition of IS 6110 in mycobacteria.
Microbiology 145, 3169-3176.
12. Dziadek, J., Sajduda, A., Dale, J.W., and McFadden, J. (1998).
IS990, a new species - specific IS - related element of the
Mycobacterium tuberculosis complex. Microb 144, 3407-3412.
13. Hernandez-Perez, Kunze, Z.M., Brown, S., Yakrus, M.A.,
McFadden, J., and Dale, J.W. (1998). Strain variation in
Mycobacterium avium: polymorphisms of IS 1110-related sequences.
International Journal of Infectious Diseases 1, 192-198.
14. Newcombe, J., Cartwright, K., Dyer, D.W., and McFadden, J.
(1998). Naturally occuring insertional inactivation of the porA gene of
Neisseria meningitidis by integration of IS 1301. Molecular
Microbiology
30, 453-454.
15. O'Donohue, M.O., Fidler, H., Garcia-Barcello, M., Norri-Aria, K.,
Williams R, and McFadden, J. (1998). Mycobacterial DNA not
detected in liver sections from patients with primary biliary cirrhosis.
Journal of Hepatology 28, 433-438.
16. Sajduda, A., Dziadek, J., Dela, A., Zalewska-Schonthaler, N.,
Zwolska, Z., and McFadden, J. (1998). DNA fingerprinting indicate
active transmission of of MDR TB in Poland. International Journal of
Infectious Diseases
3, 12-17.
17. McFadden, J. and Knowles, G. (1997). Escape from evolutionary
stasis by transposon-mediated deleterious mutations. Journal Of
Theoretical Biology
186, 441-447.
18. Newcombe, J., Dyer, S., Cartwright, K., Palmer, W.H., Blackman,
L., and McFadden, J. (1997). PCR-SSCP for non-culture-based sub-
typing of the meningococcus in clinical specimens. J.Clin.Microbiol. 35,
1809-1812.
19. Docherty, L., Adams, M.R., Patel, P., and McFadden, J. (1996). The
magnetic immuno-polymerase chain-reaction assay for the detection of
campylobacter in milk and poultry. Letts.Appl.Microbiol. 22, 288-292.
20. Newcombe, J., Palmer, W.H., Cartwright, K., and McFadden, J.J.
(1996). PCR of blood specimens for the diagnosis of meningococcal
disease. J.Clin.Microbiol. 34, 1637-1640.
21. Anthony, A., Dhillon, A.P., Fidler, H., McFadden, J.J., Billington,
O., Nygard, G., Pounder, R.E., and Wakefield, A.J. (1995).
Mycobacterial granulomatous inflamation in the ulcerated caecum of
indomethacin-treated rats. Int.J.Exp.Path. 76, 149-155.
22. Dellagostin, O.A., Esposito, G., Eales, L., Dale, J.W., and
McFadden, J. (1995). Intracellular expression and regulation of
mycobacterial promoters. Microbiology 141, 1785-1792.
23. Norman, E., Dellagostin, O.A., McFadden, J., and Dale, J.W.
(1995). Gene replacement by homologous recombination in
Mycobacterium bovis BCG. Molecular Microbiology 16, 755-760.
24. Fidler, H.M., Thurrell, W., Rook, G.A., Johnson, N.M., and
McFadden, J.J. (1994). Specific detection of Mycobacterium
paratuberculosis DNA associated with granulomatous tissue in Crohn's
disease. Gut 35, 506-510.
25. De Wit, M.Y., Douglas, J.T., McFadden, J., and Klatser, P.R. (1993).
Polymerase chain reaction for detection of Mycobacterium leprae in
nasal swab specimens. J.Clin.Microbiol. 31, 502-506.
26. Dellagostin, O.A., Wall, S., Norman, E., O'Shaughnessy, T., Dale,
J.W., and McFadden, J. (1993). Construction and use of integrative
vectors to express foreign genes in mycobacteria. Mol.Microbiol. 10,
983-993.
27. Fidler, H., Rook, G.A., Johnson, N.M., and McFadden, J.J. (1993).
Specificity of primers based on IS6110 to Mycobacterium tuberculosis
complex DNA [letter]. Tuber.Lung Dis. 74, 414-415.
28. Fidler, H., Rook, G.A., Johnson, N.M., and McFadden, J.J. (1993).
Search for mycobacterial DNA in granulomatous tissues from patients
with sarcoidosis using the polymerase chain reaction [letter; comment].
Am.Rev.Respir.Dis. 147, 777-778.
29. Fidler, H.M., Ibbotson, J., Chahal, H., Mussaddeq, Y., Allan, R.N.,
Johnson, N.M., and McFadden, J.J. (1993). Abdominal lymph-node
granulomas and Helicobacter pylori [letter; comment]. Lancet 342, 299-
300.
30. Fidler, H.M., Rook, G.A., McI, W., Johnson, N.M., and McFadden,
J.J. (1993). The demonstration of Mycobacterium tuberculosis DNA in
tissue affected by sarcoidosis. Br.Med.J. 306, 546-549.
31. McFadden, J., Collins, J., Beaman, B., Arthur, M., and Gitnick, G.
(1993). Mycobacteria in Crohn's disease: DNA probes identify the
wood- pigeon strain of Mycobacterium avium in Crohn's disease tissue.
J.Clin.Microbiol. 30, 3070-3073.
32. McFadden, J.J. (1993). Abolish Mycobacterium paratuberculosis
strain 18 [letter] J.Clin.Microbiol. 31, 1958.
33. Wall, S., Kunze, Z.M., Saboor, S., Soufleri, I., Seechurn, P.,
Chiodini, R., and McFadden, J.J. (1993). Identification of spheroplast-
like agents isolated from tissues of patients with Crohn's disease and
control tissues by polymerase chain reaction. J.Clin.Microbiol. 31,
1241-1245.
34. Knight, A.I., Ni, H., Cartwright, K.A.V., and McFadden, J.J. (1992).
Isolation and characterization of a novel insertion sequence, IS1106, downstream of the porA gene in B15 Neisseria meningitidis.
Mol.Microbiol. 6, 1565-1573.
35. Kunze, Z.M., Portaels, F., and McFadden, J.J. (1992). Biologically
distinct subtypes of Mycobacterium avium differ in possession of
insertion sequence IS901. J.Clin.Microbiol. 30, 2366-2372.
36. Ni, H., Knight, A.I., Cartwright, K.A.V., and McFadden, J.J. (1992).
Phylogenetic and epidemiological analysis of Neisseria meningitidis
using DNA probes. Epidem.Infect. 109, 227-239.
37. Ni, H., Knight, A.I., Palmer, W.H., Cartwright, K., and McFadden, J.
(1992). PCR in the diagnosis of meningococcal meningitis. Lancet 340,
1432-1434.
38. Saboor, S., Johnson, N.J., and McFadden, J.J. (1992). Detection of
mycobacteria in sarcoidosis and tuberculosis with polymerase chain
reaction. Lancet 339, 1012-1015.
39. England, P.M., Wall, S., and McFadden, J.J. (1991). IS900-promoted
stable integration of a foreign gene into mycobacteria. Molecular
Microbiology
5, 2047-2052.
40. Kunze, Z.M., Wall, S., Appelberg, R., Silva, M.T., Portaels, F., and
McFadden, J.J. (1991). IS901, a new member of a widespread class of
atypical insertion sequences, is associated with pathogenicity in
Mycobacterium avium. Molecular Microbiology 5, 2265-2272.
41. Portaels, F., Kunze, Z.M., McFadden, J.J., Fonteyne, P.A., and
Carpels, G. (1991). AIDS and mycobacterial diseases in developing
and developed countries. J.Chemoth. Suppl. 4, 449-450.
42. Knight, A.I., Cartwright, K.A.V., and McFadden, J.J. (1990).
Identification of a UK outbreak strain of Neisseria meningitidis with a
DNA probe. Lancet 335, 1182-1184.
43. Portaels, F., Kunze, Z.M., McFadden, J.J., Fonteyne, P.A., and
Carpels, G. (1990). Mycobacterial disease in AIDS patients from
developing and developed countries. Tagen de Tuberculose 2, 67-71.
44. Vary, P.H., Andersen, P.R., Green, E., Hermon-Taylor, J., and
McFadden, J.J. (1990). Use of highly specific DNA probes and the
polymerase chain reaction to detect Mycobacterium paratuberculosis in
Johne's disease. J.Clin.Microbiol. 28, 933-937.
45. Cooper, G.L., Grange, J.M., McGreggor, J.A., and McFadden, J.J.
(1989). The potential use of DNA probes to identify and type strains
within the Mycobacterium tuberculosis complex. Letts.Appl.Microbiol.
8, 127-130.
46. Green, E.P., Tizard, M.L.V., Moss, M.T., Thompson, J.,
Winterbourne, D.J., McFadden, J.J., and Hermon-Taylor, J. (1989).
Sequence and characteristics of IS900, and insertion element identified
in a human Crohn's disease isolate of Mycobacterium paratuberculosis.
Nucl.Acids Res. 17, 9063-9073.
47. Hampson, S., Parker, M., Saverymuttu, S., Joseph, A.E.J.,
McFadden, J.J.J., and Hermon-Taylor, J.J. (1989). Quadrupal
antimicrobial therapy in Crohn's disease: Results at 9 months of a pilot
study in 20 patients. Aliment.Pharmacol.Med. 3, 343-352.
48. Hampson, S.J., Portaels, F., Thompson, J., Green, E.P., Moss,
M.T., Hermon-Taylor, J., and McFadden, J.J. (1989). DNA probes
demonstrate a single highly conserved strain of Mycobacterium avium
infecting AIDS patients. Lancet i, 65-68.
49. McFadden, J.J., Banerjee, D., and Stanford, J. (1989). Use of DNA
probes to investigate the genetics of Mycobacterium leprae.
International Journal of Leprosy 57, 328-329.
50. Visuvanathan, S., Moss, M.T., Stanford, J.L., Hermon-Taylor, J.,
and McFadden, J.J. (1989). Simple enzymic method for isolation of
DNA from diverse bacteria. J.Microbiol.Methods 10, 59-64.
51. Butcher, P.D., McFadden, J.J., and Hermon-Taylor, J. (1988).
Investigation of mycobacteria in Crohn's disease tissue by Southern
blotting and DNA hybridisation with cloned mycobacterial genomic DNA
probes from a Crohn's disease isolated mycobacteria. Gut 29, 1222-
1228.
52. Hampson, S. and McFadden, J.J. (1988). Use of cloned
mycobacterial specific DNA probes to examine mycobacteria derived
from AIDS patients. Gastroenterology 94, 170-170.
53. Hampson, S.J., McFadden, J.J., and Hermon-Taylor, J. (1988).
Mycobacteria and Crohn's disease. Gut 29, 1017-1019.
54. McFadden, J.J. and Houdayer, C. (1988). No evidence for
antibodies to mycobacterial A60 antigen in Crohn's disease sera by
enzyme-linked immunoabsorbent assay. J.Med.Microbiol. 25, 295-298.
55. McFadden, J.J. and Thompson, J. (1988). Identification and
characterisation of further bacteria isolated from Crohn's disease and
control tissue. Gastroenterology 94, 294-294.
56. McFadden, J.J., Butcher, P.D., Chiodini, R.J., and Hermon-Taylor,
J. (1987). Determination of genome size and DNA homology between
an unclassified Mycobacterium species isolated from patients with
Crohn's disease and other mycobacteria. Journal of General
Microbiology
133, 211-214.
57. McFadden, J.J., Butcher, P.D., Thompson, J., Chiodini, R.J., and
Hermon-Taylor, J. (1987). The use of DNA probes identifying
restriction-fragment-length polymorphisms to examine the
Mycobacterium avium complex. Molecular Microbiology 1, 283-291.
58. McFadden, J.J., Butcher, P.D., Chiodini, R.J., and Hermon-Taylor,
J. (1987). Crohn's disease-isolated mycobacteria are identical to
Mycobacterium paratuberculosis, as determined by DNA probes that
distinguish between mycobacterial species. J.Clin.Microbiol. 25, 796-
801.
59. Butcher, P.D., McFadden, J.J., and Hermon-Taylor, J. (1986). The
electrophoretic analysis of low molecular weight nucleic acids from
Crohn's disease in the search for an unconventional small infectious
agent. Arch.Virol. 88, 113-120.
60. Butcher, P.D., McFadden, J.J., Murray, A., and Hermon-Taylor, J.
(1985). Immunoprecipitation of antigen-associated [32P]-labelled
nucleic acids from Crohn's disease mesenteric lymph nodes.
Br.J.Exp.Pathol. 66, 679-687.
61. McFadden, J.J., Butcher, P.D., Winterbourne, D., and Hermon-
Taylor, J. (1985). No evidence for common cellular antigens recognised
by Crohn's disease sera. J.Clin.Lab.Immunol. 18, 87-90.
62. Davies, K.E., Schull, S., Donald, J.A., McFadden, J.J., and et al
(1984). The isolation of DNA linkage markers for chromosome 19.
Cytogenet.Cell.Genet. 37, 448-448.
63. Humphries, S.E., Donald, J.A., McFadden, J.J., Shull, S.,
Williamson, R., Jowett, N., and et al (1984). The use of polymorphic
DNA and protein markers for the third complement component for
detecting linkage of famial hypercholesterolaemia. Artheros. 52, 267-
278.
64. McGinty, R.M., McFadden, J.J., Rawlinson, C.J., and Buck, K.W.
(1984). Widespread inhibitor production in culture by isolates of
Gaemannomyces graminis var tritici. Trans.Br.Mycol.Soc. 82, 429-434.
65. McFadden, J.J., Buck, K.W., and Rawlinson, C.J. (1983).
Infrequuent transission of double-stranded RNA virus particles but
absence of DNA provirus in single ascospore cultures of
Gaeumannomyces graminis. J.Gen.Virol. 64, 927-937.
66. McFadden, J.J. and Buck, K.W. (1983). Sequence complexities of
the nuclear and mitochondrial genomes of the take-all fungus,
Gaeumannomyces graminis. J.Gen.Microbiol. 129, 3515-3518.
67. Buck, K.W., Almond, M.R., McFadden, J.J., and Rawlinson, C.J.
(1981). Properties of thirteen viruses and virus variants obtained from
eight isolates of the wheat take-all fungus Gaeumannomyces graminis
var tritici. J.Gen.Virol. 57, 157-168.
68. Buck, K.W., Romanos, M.A., McFadden, J.J., and Rawlinson,
C.J. (1981). In-vitro transcription of double-stranded RNA by virion-
associated RNA polymerases of viruses of Gaeumannomyces graminis.
J.Gen.Virol. 53, 235-245.

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