Septanest 1:100,000
Driving or operating machinery
If you experience unwanted effects, including dizziness or blurred Articaine hydrochloride 4% with adrenaline
vision, you should not drive or operate machinery until these effects (epinephrine) injection 1:100,000
How this medicine will be used
Septanest 1:200,000
Your dentist will explain to you why you are being treated withSEPTANEST and tell you which formula and what dose you will be Articaine hydrochloride 4% with adrenaline
administered. One cartridge is usually sufficient but your dentist maygive you a greater quantity. He chooses the formula and adjusts the (epinephrine) injection 1:200,000
dosage according to your age, to your health and to the dental work.
SEPTANEST 1:200,000 is usually used for simple and short dental works.
SEPTANEST 1:100,000 is more adapted to procedures lasting longer or PATIENT INFORMATION LEAFLET
Please read this leaflet carefully before you start using this What to do if an overdose is taken
medicine. It tells you the important points you should knowabout SEPTANEST.
If you think you may have been given too much of this injection and feel Pharmaceutical form
Unwanted effects
What's in your medicine
SEPTANEST like most other medicines, may cause side effects insome patients. Although not all of these side effects may occur, if they Each ml of solution for injection contains 40.00 mg of articaine do occur they may need medical attention. While you are in your dentist office, your dentist will carefully follow the effects of SEPTANEST.
- 18.2 micrograms of adrenaline (epinephrine) as the acid tartrate However, some effects may not be noticed or appear later. Check with your (10.00 micrograms expressed as base) for SEPTANEST 1:100,000.
dentist, doctor or pharmacist if any of the following side effects occur : - 9.1 micrograms of adrenaline (epinephrine) as the acid tartrate (5.00 - you are feeling nervous, nauseous or dizzy, micrograms expressed as base) for SEPTANEST 1:200,000.
It is a clear and colourless solution.
- you are trembling, have buzzing in the ears, blurred vision or have It also includes the following inactive ingredients: sodium metabisulphite, any abnormal feeling, yawning, problems with speech, shaking, sodium chloride, sodium hydroxide and water for injections.
SEPTANEST is available in boxes containing 50 cartridges of 1.7 ml or of 2.2 ml.
- your heart is beating slowly or irregularly,- you have facial swelling or inflammation of gums, Name of marketing authorisation holder: Septodont UK Ltd, Units R & S - you have skin rash, hives or itching or severe allergic reaction, - Orchard Business Centre - St Barnabas Close -Allington, Maidstone, Kent - you may have a loss of sensation and muscle function following the injection of SEPTANEST. Resolution occurs generally within eight weeks.
Name of manufacturer: Septodont, 58 rue du Pont de Créteil, 94100 You may be hypersensitive to sulphites and therefore show allergic symptoms to SEPTANEST as respiratory or skin reactions.
About your medicine
If you have problems with the blood supply to your arms and/or legs orhigh blood pressure this medicine may result in a small injury at the site SEPTANEST is given by injection to cause loss of feeling before and during dental procedures. It contains two active ingredients: articaine Patients who already have a condition of the blood called hydrochloride, a local anaesthetic which prevents pain, and adrenaline methaemoglobinaemia may find they become worse.
tartrate, a vasoconstrictor which makes the effect last longer(Adrenaline narrows the blood vessels at the site of injection, which keeps the anaesthetic where needed for a longer time) and controls the Your dentist will not use this medicine if its colour is pinkish or darker than slightly yellow of if it contains a precipitate.
Before this medicine is used
SEPTANEST 1:100,000 and 1:200,000 contain less than 1 mmolsodium (0.058 mmol/ 1.7 ml or 0.075 mmol/ 2.2 ml), i.e. essentially SEPTANEST is not for use in children of less than 4 years.
SEPTANEST contains sodium metabisulphite (E 223). Sodium Storing your medicine
metabisulphite can cause allergic-type reactions including anaphylacticsymptoms and bronchospasm (difficulty in breathing) in some people. If It is most unlikely that you will be asked to look after this medicine. Your you suffer from allergy or asthma this is more likely to happen.
dentist will keep it up to 25° C, stored in the original container (protected Before receiving this medicine, tell your dentist if: from light). It should not be frozen. He will not use this medicine after - you are allergic to local anaesthetics or any particular ingredients, the expiry date printed on the package.
- you are asthmatic or have suffered difficulty with your breathing as a All medicines must be kept in a safe place out of the reach of children.
result of taking medicines which contain ingredients called sulphites Further information
- you are taking antidepressant treatment or have taken such a drug Remember this medicine is only for you. Only a dentist can administer - you have problems in the way your muscles work by not having This leaflet provides only a summary of the information enough of a substance called cholinesterase in your body, known about SEPTANEST. If you have any questions, - you have problems with your heart, your blood vessels, your heart want to know more about this medicine, or have some Date of preparation: September 2004.
If more PILs are necessary, call free number 0800
- you have diabetes or have an overactive thyroid gland, whether or not There are medicines which should not be given with SEPTANEST or whichshould be used with caution as ß-blocking agents (e.g. propranolol), cardiac glycosides (e.g. digoxin) and vasopressor drugs (e.g. dihydroergotamine).
Please make sure that you tell your dentist about all medicines which you are taking, whether prescribed or purchased.
58, rue du Pont de Créteil.
94100 Saint-Maur-des-Fossés, France.


Microsoft word - nvpo.doc

PRISE EN CHARGE DES NAUSEES ET VOMISSEMENTS POST-OPERATOIRES Validation par Dr E. AHLSCHWEDE Dr. MOULLIER chef de service d’anesthésie M. LAURENCIN président COMEDIMS DIFFUSION: services de chirurgie et de gynécologie – obstétrique, service d’anesthésie 1. OBJECTIFS : Traitement et prophylaxie des nausées et vomissements post-opératoires (NVPO).

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