CHEWABLES FOR CATS
Federal (USA) law restricts this drug to use by or on the order of
delayed, whether by a few days or many, immediate treatment with
HEARTGARD for Cats and resumption of the recommended dosing regimenwill minimize the opportunity for development of adult heartworm.
For use in cats to prevent feline heartworm disease by
eliminating the tissue stage of heartworm larvae (Dirofilaria immitis
) for a
It is recommended that cats should be tested for existing heartworm
month (30 days) after infection, and for the removal and control of adult and
infection prior to starting treatment with HEARTGARD for Cats. Cats already
immature hookworms (Ancylostoma tubaeforme
and A. braziliense
infected with adult heartworms can be given HEARTGARD for Cats monthlyto prevent further infections.
HEARTGARD® (ivermectin) for Cats should be administered orally
at monthly intervals at the recommended minimum dose level of 24 mcg of
Monthly treatment with HEARTGARD for Cats also provides effective
ivermectin per kg (10.9 mcg/lb.) of body weight. The recommended dosage
removal and control of adult and immature hookworms (A. tubaeforme
schedule for prevention of feline heartworm disease and control of
In the clinical studies involving more than 3000 doses of
HEARTGARD for Cats, observations reported within 24 hours of treatment
HEARTGARD for Cats
included vomition in ≤ 0.3% and diarrhea in ≤ 0.2% of the doses
Chewables per month
administered. There were no statistical differences between HEARTGARD
for Cats and the product vehicle (control) for these observations.
A wide margin of safety was demonstrated in clinical trials at therecommended dose level in cats and kittens 6 weeks of age and older and in
For cats over 15 lb., use the appropriate combination of chewables.
laboratory studies in cats with circulating microfilariae of D. immitis.
margin of safety has also been demonstrated at 3 times the recommended
HEARTGARD for Cats is recommended for use in cats 6 weeks of age and older.
dose in pregnant or breeding queens and breeding toms. No adverse effectswere observed in either male or female cats or their offspring in breeding
Remove only one chewable at a time from the foil-
studies. A 30-fold safety margin over the minimum recommended dosage
backed blister card. Return the card with the remaining chewables to its box
was established in a single dose tolerance study. In growing kittens dosed
to protect the product from light. HEARTGARD for Cats can be offered to the
monthly for 8 consecutive doses, one cat given 5 times the market dose
cat by hand or may be added to a small amount of cat food. If manual dosing
vomited and a second cat in this group experienced diarrhea within 24 hours
is required, the chewable should be broken into pieces for administration.
of the initial treatment. In clinical trials, many commonly used flea control
Food should be routinely available during the day of treatment administration.
products, anthelmintics, vaccines, antibiotics and steroid preparations were
If cats are fasted, or if the chewable is not broken into pieces for manual
administered with HEARTGARD for Cats without incident.
dosing, then reduced absorption may result. A relationship between reducedabsorption and reduced efficacy has not been established.
Keep this and all drugs out of the reach of children.
In case of
ingestion by humans, clients should be advised to contact a physician
Care should be taken to see that the cat consumes the complete dose.
Treated animals should be observed for a few minutes after administrationto ensure that part of the dose is not lost or rejected. If it is suspected that
HEARTGARD Chewables for Cats are stable for 3 years when
any of the dose has been lost, redosing with a new chewable is recommended.
stored below 77°F (25˚C) and protected from light. Store at controlled room
Fragments of chewables have occasionally been observed in the feces of
temperature of 68°F - 77°F (20°C - 25°C). Excursions between 59°F - 86°F (15°C -
some cats; efficacy of the product was not adversely affected.
HEARTGARD for Cats should be given at monthly intervals when mosquitoes
HEARTGARD for Cats is available in two dosage
potentially carrying infective heartworm larvae are active. The initial dose
strengths (see DOSAGE section) for cats of different weights. Each strength
must be given within a month (30 days) after the cat’s first exposure to
comes in a convenient carton of 6 chewables, packed 10 cartons per tray.
mosquitoes. The final dose must be given within a month (30 days) after thecat’s last exposure to mosquitoes. For optimal performance, HEARTGARD for
For customer assistance, please contact Merial at 1-888-637-4251.
Cats must be given once a month on or about the same date. If treatment is
®HEARTGARD and the Cat & Hand Logo are registered trademarks of Merial. 2011 Merial Limited, Duluth, GA. All rights reserved.
3/2. Multiple Choice The following questions have one or more correct answers. Use the notations given below: A: only the 1st , 2nd and 3th are correct B: only the 1st and 3th are correct C: only the 2nd and 4th answers are correct D: only the 4th answers is correct E: all of the answers are correct 131. Choose the compounds whose UV spectra display a significant shift u
P – Akhtar everyone calls her. Akhtar which is AKHTAR. P – and that’s in Langroud, a little town in North of Iran. That’s around Caspian Sea, northof Iran. Both your own family and when you were younger, so how many in your family?P – My mother’s got two sisters and one brother. She’s got two sons and one daughter. And where were you in the family, which number?P – Her brother